Показати скорочений опис матеріалу

dc.creatorBystrytska, M. A.
dc.date2018-07-25
dc.date.accessioned2020-07-03T09:39:57Z
dc.date.available2020-07-03T09:39:57Z
dc.identifierhttps://ojs.tdmu.edu.ua/index.php/ijmr/article/view/8701
dc.identifier10.11603/ijmmr.2413-6077.2018.1.8701
dc.identifier.urihttps://repository.tdmu.edu.ua/handle/123456789/16452
dc.descriptionBackground. The study of late complications, including osteoporosis, is urgent due to the increasing life expectancy of patients with complete spinal cord injury (SCI). Objective. The aim of the study is to evaluate bone mineral status and bone turnover markers in the patients with chronic SCI.Methods. 73 SCI patients and 57 healthy persons were examined. Bone status was determined by ultrasound (US) densitometry. Bone turnover markers and vitamin D were evaluated by electrochemiluminescence method.Results. In the SCI patients bone mineral status was significantly lower compared with the individuals of control group. The stiffness index (SI) was 51.4±11.8 % vs. 98.5±16.6 %, p<0.05 in men and 50.1±9.8 % vs. 92.9±11.1 %, p<0.05 in women. In the SCI patients the levels of bone turnover markers were significantly higher than the reference values. The bone mineral status of patients with SCI, which occurred before peak bone mass development, is significantly worse, compared with the individuals with the already developed peak bone mass, that makes them a high risk group for fracture. Conclusions. SCI leads to increased bone resorption with development of secondary osteoporosis (according to the ultrasound densitometry of calcaneal bone). In chronic SCI, bone resorption is higher than in the individuals with combined low levels of vitamin D, and the absence of axial load results in continued loss of bone mass.en-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherI. Horbachevsky Ternopil National Medical Universityen-US
dc.relationhttps://ojs.tdmu.edu.ua/index.php/ijmr/article/view/8701/8560
dc.sourceInternational Journal of Medicine and Medical Research; Vol. 4 No. 1 (2018): International Journal of Medicine and Medical Research; 21-25en-US
dc.sourceInternational Journal of Medicine and Medical Research; Том 4 № 1 (2018): International Journal of Medicine and Medical Research; 21-25ru-RU
dc.sourceInternational Journal of Medicine and Medical Research; Том 4 № 1 (2018): International Journal of Medicine and Medical Research; 21-25uk-UA
dc.source2414-9985
dc.source2413-6077
dc.source10.11603/ijmmr.2413-6077.2018.1
dc.subjectspinal cord injuryen-US
dc.subjectosteoporosisen-US
dc.subjecttetraplegiaen-US
dc.subjectparaplegiaen-US
dc.subjectbone turnover markersen-US
dc.subjectultrasound densitometry.en-US
dc.titleBONE MINERAL STATUS AND METABOLISM DISORDERS IN PATIENTS WITH CHRONIC SPINAL CORD INJURYen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


Долучені файли

ФайлРозмірФорматПереглянути

Даний матеріал не має долучених файлів.

Даний матеріал зустрічається у наступних фондах

Показати скорочений опис матеріалу