Neurotropic, Hormonal and Immunotropic Activity of Uric Acid :

Abstract

This monograph presents the results of priority experimental and clinical-physiological research on the associations of uricemia, uricosuria with parameters of urea, creatinine, electrolyte exchange, as well as the nervous, endocrine and immune system. In line with the concepts of the neuroendocrine-immune complex and the functional-metabolic continuum, by discriminant and canonical correlation analyses, it has been established that the uric acid molecule exhibits significant physiological activity and can be considered the fourth endogenous signaling molecule alongside NO, CO, and H2S. For biochemists, pathophysiologists, neurologist, endocrinologists, and immunologists.