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LEFT VENTRICULAR DIASTOLIC DYSFUNCTION AND OXYGEN SUPPLY OF LOWER EXTREMITIES IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE AND CONCOMITANT TYPE 2 DIABETES MELLITUS

dc.creatorYarema, N. I.
dc.creatorPasyechko, N. V.
dc.creatorKhomitska, A. I.
dc.creatorSavchenko, I. P.
dc.creatorSmachylo, I. V.
dc.creatorNaumova, L. V.
dc.creatorRadetska, L. V.
dc.creatorBob, A. O.
dc.creatorHavrylyuk, M. E.
dc.creatorBob, O. O.
dc.creatorHavrylyuk, N. M.
dc.creatorKotsyuba, O. I.
dc.date2017-12-29
dc.date.accessioned2020-07-03T09:39:55Z
dc.date.available2020-07-03T09:39:55Z
dc.identifierhttps://ojs.tdmu.edu.ua/index.php/ijmr/article/view/8242
dc.identifier10.11603/ijmmr.2413-6077.2017.2.8242
dc.identifier.urihttps://repository.tdmu.edu.ua/handle/123456789/16444
dc.descriptionBackground. The peculiarities of diastolic heart failure and indices of arterial and venous blood oxygenation in patients with stable ischemic heart disease and concomitant type 2 diabetes mellitus are presented in the article. Obvious left ventricular diastolic dysfunction with the increased levels of natriuretic peptide, uric acid and decreased indices of arterial and venous blood oxygenation in the presence of comorbid type 2 diabetes mellitus have been revealed.Objective. The research was aimed to study the peculiarities of left ventricular diastolic function disorders, levels of NT-proBNP, uric acid and indices of arterial and venous blood oxygenation in patients suffering from stable exertional angina with underlying comorbid type 2 diabetes mellitus.Methods. 70 patients with IHD: stable exertional angina of the ІІІ functional class, were examined. The first group comprised 39 patients with stable exertional angina of the ІІІ functional class with left ventricular diastolic dysfunction; the second group – 31 patients with stable exertional angina of the ІІІ functional class with left ventricular diastolic dysfunction and concomitant type 2 diabetes mellitus. All the examined patients underwent BD- echocardioscopy, with the detailed evaluation of left ventricular diastolic function, NT-proBNP and uric acid levels in venous blood were determined by immunoenzyme method, indices of arterial and venous blood oxygenation were evaluated too.Results. The correlation between left ventricle diastolic function and oxygen volume consumed by the tissues of lower extremities in patients with stable ischemic heart disease and concomitant type 2 diabetes mellitus was determined.Conclusions. In patients with stable IHD, left ventricular diastolic dysfunction and concomitant type 2 diabetes mellitus the levels of NT-proBNP, uric acid and oxygen supply of lower extremities are significantly higher as compared to patients with IHD without type 2 diabetes mellitus.en-US
dc.formatapplication/pdf
dc.formatapplication/vnd.openxmlformats-officedocument.wordprocessingml.document
dc.formatapplication/vnd.openxmlformats-officedocument.wordprocessingml.document
dc.languageeng
dc.publisherI. Horbachevsky Ternopil National Medical Universityen-US
dc.relationhttps://ojs.tdmu.edu.ua/index.php/ijmr/article/view/8242/7766
dc.relationhttps://ojs.tdmu.edu.ua/index.php/ijmr/article/view/8242/8833
dc.relationhttps://ojs.tdmu.edu.ua/index.php/ijmr/article/view/8242/8834
dc.sourceInternational Journal of Medicine and Medical Research; Vol. 3 No. 2 (2017): International Journal of Medicine and Medical Research; 16-19en-US
dc.sourceInternational Journal of Medicine and Medical Research; Том 3 № 2 (2017): International Journal of Medicine and Medical Research; 16-19ru-RU
dc.sourceInternational Journal of Medicine and Medical Research; Том 3 № 2 (2017): International Journal of Medicine and Medical Research; 16-19uk-UA
dc.source2414-9985
dc.source2413-6077
dc.source10.11603/ijmmr.2413-6077.2017.2
dc.subjectstable ischemic heart diseaseen-US
dc.subjectleft ventricular diastolic dysfunctionen-US
dc.subjectdiabetes mellitusen-US
dc.subjectnatriuretic peptideen-US
dc.subjectblood oxygenation.en-US
dc.titleLEFT VENTRICULAR DIASTOLIC DYSFUNCTION AND OXYGEN SUPPLY OF LOWER EXTREMITIES IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE AND CONCOMITANT TYPE 2 DIABETES MELLITUSen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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